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For centuries, middle-aged women have used herbs that contain phytoestrogens, including dong quai (angelica), licorice root, chaste berry, black cohosh, false unicorn root, and fennel. Femtrol combines standardized extracts of these plants with ascorbic acid (vitamin C) and hesperidin (bioflavonoids). Vitamin C and bioflavonoids are highly concentrated in the ovaries.